She has also notched up more hits than The Beatles, popularised the Gaultier cone bra and broken the taboo around older women’s sexuality.
In the process, Madonna, now 64, has cheesed off everyone from Pope John Paul II to Camille Paglia via US Superbowl bosses.
But, as this new rainbow-vinyl remix version of her career-spanning 6xLP collection Finally Enough Love: Fifty Number Ones reminds us, the music is what really counts.
It kicks off with the early trinity of corkers – 1983’s Holiday and 1984’s Like A Virgin and Material Girl.
Then comes the You Can Dance remix of 1985’s Into The Groove, the first of dozens of reworkings by world-class producers including Honey Dijon, Shep Pettibone and Avicii, all remastered by Madame X producer Mike Dean.
The compilation packs in more than 220 minutes of club chart-topping dance, with guest appearances from Britney (Me Against The Music), Nicki Minaj (Bitch I’m Madonna) and Justin Timberlake and Timbaland (4 Minutes).
We get the infectious “Miami remix” of Don’t Cry For Me
Argentina and a gloriously carefree party rock rejig of 2012’s Give Me All Your Luvin’ (featuring LMFAO and Nicki Minaj).
Madge’s first single, 1982’s Everybody (not included, it only reached No3), demonstrated a devotion to disco and dance that never faded.
1990’s multi-platinum Vogue borrowed from Raw Silk’s Do It To The Music and Salsoul Orchestra’s Ooh I Love It.
2005’s global chart-topper Hung Up incorporated an Abba riff (with their approval).
In the 90s, she made electronica mainstream with spellbinding hit Frozen.
This boxset isn’t cheap (£128.99) but it shows why Michigan-born Madonna is comfortably the biggest-selling female artist of all time.
The Queen of Pop has proved invulnerable to everything except maybe film critics.
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